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NEXGARD

FDA Application Number: 141-406

Based on the FDA Center for Veterinary Medicine data from November 2013 to March 2025: Of 1,547 reported animal deaths involving NEXGARD, 855 occurred when NEXGARD was the only drug administered - representing 55% of all fatalities.

55%
of reported fatalities involved only NEXGARD
46,892
Total Animals Reported
1,547
Total Fatalities
855
Single-Drug Fatalities

Top 3 Reported Adverse Events

Vomiting
Lethargy (See Also Central Nervous System Depression in Neurological)
Diarrhea

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All data is sourced from the FDA Center for Veterinary Medicine adverse event reports submitted voluntarily by veterinarians, pet owners, and drug manufacturers. This information has not been independently verified and does not establish that any drug caused the reported outcomes. These reports reflect what was submitted to the FDA, not confirmed cause-and-effect relationships or actual risk rates. Reporting rates may vary by drug, manufacturer, and time period, and may be delayed up to 6 months. The percentage shown represents proportions within the reported dataset and does not indicate risk probability or safety ratings. SafeVetMeds is a 501(c)(3) nonprofit providing data transparency infrastructure and does not provide veterinary medical advice, diagnostic services, or legal counsel. For medical decisions regarding your animal, consult a licensed veterinarian. For legal questions, consult an attorney. This data should be considered as one factor among many in medical decision-making, not as definitive evidence of drug safety or danger.